The University of Arizona

Arizona Center for Integrative Medicine

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Ongoing Research Projects

NASA - Johnson Space Center (JSC)

CHIP and NASA are co-developing a "National Assessment of Stress Adaptation" (NASA2) which is a state of the art, online assessment of worksite stress focusing on individual, organizational, and environmental factors. The primary objective of the project is to develop and validate a "Worksite Climate Assessment" instrument for NASA.  Upon completion NASA2 is a precursor to identify areas for subsequent intervention studies.

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Prudential Associates are empowered to address their healthcare resource needs when facing the prospect of work disability through focused, professional employer-based advocacy in This study with Prudential is designated as the "Supporting Total Recovery In Valued Employees" (STRIVE) pilot research project. In STRIVE, the objective is to develop and evaluate an integrative medicine approach to the management of disabilities for Prudential's own employees. A new, comprehensive, early intervention model is being tested with both clinical and cost outcomes.

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University of Arizona School of Medicine & The Marino Center of Integrative Medicine

"Studies in Patient-Based Informatics for Comparative Effectiveness Research" (SPICER).  In recent times, comparative effectiveness research (CER) has been taken to mean conventional randomized clinical trials (RCTs). It has been increasingly recognized, however, that RCTs work best in the case of narrowly-defined populations over relatively short time periods, for testing interventions that are easy to specify and deliver. Since both integrative medicine (IM) as well as clinical and community-based complementary and alternative medicine (CAM) frequently have none of these characteristics, it is natural to turn to other sources for CER. An obvious alternative consists of existing electronic medical records (EMR). It is, however, not true that the enormous volume of these records can be easily mobilized to answer clinical research questions. Applying the statistical methods of RCTs to clinical observational data is frequently a mistake, as any number of studies have asserted. It does not follow from this, however, that EMR data is of no clinical research use – instead the implication is that the statistical methods need to be modified. The focus of this proposal is to create a model project to establish the protocols, based on previously developed methods, by which clinical research from existing data (perhaps modestly supplemented with new data acquisition) can be envisioned, designed, carried out, and analyzed. The long-term goal of the project is to scale this model up to multiple clinics, cumulating an ever larger and more research-useful database for a broad variety of both disease states and therapeutic approaches, which provides patient-centered evidence-based recommendations that apply to the populations of patients who actually present themselves for medical care.

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